John Napoli
John presents a practical, structured approach to integrating AI into business operations using an AI Factory framework, with a clear 'out of the box' roadmap for AI adoption for enterprises.
John Napoli is a highly-technical thought leader with a history of empowering the future for some of the most systemically significant financial firms in the world, driving continuous improvement, and reliably running effective organizations. He consistently bridges the gap between business value and innovation via Global Technology (CIO/CTO), Business Transformation, Data & Analytics (CDO/CDAO), Operations, Finance (CFO), Board Membership, and Strategic Investment. John is focused on diverse solutions including artificial intelligence & machine learning, data management, the cloud, the engineer experience, service management, blockchain, quantum, low code, cybersecurity, automation, business process re-engineering, and more.
John is currently the Founder and CEO of MissonLabs.ai., with a mission to empower businesses and organizations to thrive in the age of artificial intelligence. The company provides expert AI consulting services that guide our clients through the complexities of AI adoption, helping them unlock innovative solutions and drive operational excellence. In addition to consulting expertise, the company actively invests in cutting-edge AI technologies and startups, fostering the next generation of intelligent solutions.
Prior to MissionLabs.ai, John was the Chief Transformation and Artificial Intelligence Officer for Guardian Life Insurance (GLIC) from 2023–2025. Guardian is a 160-year-old Fortune 250 company with over $800 billion in life insurance in force, $95 billion in assets under management, and $11 billion in capital, as of February 2025.
In this role, John partnered with the businesses to spearhead enterprise transformation, automation, transparency, and strategic execution to continuously improve delivery, reduce waste, increase productivity, and ultimately positively impact GLIC's bottom line.
Previously, John was with J.P. Morgan Chase's (JPMC) from 2013–2023 in several senior leadership positions of increasing responsibility. As Chief Operating Officer of Chief Technology and Data Offices, he was responsible for overseeing the firmwide strategy, governance, and risk & control guardrails for the firm's public cloud and artificial intelligence & machine learning platforms.
As Chief Operating Officer (COO) of Global Technology (GT) and Chief Information Office (CIO) from 2018–2020, John oversaw Global Technology Strategy, established an Office of the CIO to bring structure and repeatability to the complex CIO role, and standardizing Executive Management Reporting. As CFO, COO, & Head of Strategy, Asset & Wealth Management (AWM) Technology, Operations, & Digital (2014–2018), he led a team of ~150 individuals, helped to orchestrate a >$2.0 billion global budget covering >10,000 in headcount, in >50 locations, with ~700 applications, and >175 vendors.
From 2009–2013 at German multinational investment bank and financial services company Deutsche Bank (NYSE: DB), John held a number of technology and COO leadership positions.
John began his career with Broadridge and the New York Stock Exchange (SIAC); as a management and technology consultant; as a financial services lead for a technology company, BEA Systems (acquired by Oracle); and as a founder of a related system integration firm, Prime Business Consulting.
John graduated with a Masters of Business Administration in Finance & Management and Masters of Science in Computer Science from New York University, as well as a Bachelor of Science, Computer Science from Georgetown University. John is also a certified AWS Machine Learning Specialist, AWS Cloud Solutions Architect, and Scaled Agile Framework (SAFe) 5 Agilist. He is 2025 #1 Amazon Best Selling author of AI: Achieving Impact: Implementing Enterprise AI Via an AI Factory.
He lives in Stamford, CT with his 19- and 17-year-old daughters and his 14-year-old son. He enjoys skiing, sailing, and maximizing his time with friends and family when not at work.
John Napoli is a highly-technical thought leader with a history of empowering the future for some of the most systemically significant financial firms in the world, driving continuous improvement, and reliably running effective organizations. He consistently bridges the gap between business value and innovation via Global Technology (CIO/CTO), Business Transformation, Data & Analytics (CDO/CDAO), Operations, Finance (CFO), Board Membership, and Strategic Investment. John is focused on diverse solutions including artificial intelligence & machine learning, data management, the cloud, the engineer experience, service management, blockchain, quantum, low code, cybersecurity, automation, business process re-engineering, and more.
John is currently the Founder and CEO of MissonLabs.ai., with a mission to empower businesses and organizations to thrive in the age of artificial intelligence. The company provides expert AI consulting services that guide our clients through the complexities of AI adoption, helping them unlock innovative solutions and drive operational excellence. In addition to consulting expertise, the company actively invests in cutting-edge AI technologies and startups, fostering the next generation of intelligent solutions.
Prior to MissionLabs.ai, John was the Chief Transformation and Artificial Intelligence Officer for Guardian Life Insurance (GLIC) from 2023–2025. Guardian is a 160-year-old Fortune 250 company with over $800 billion in life insurance in force, $95 billion in assets under management, and $11 billion in capital, as of February 2025.
In this role, John partnered with the businesses to spearhead enterprise transformation, automation, transparency, and strategic execution to continuously improve delivery, reduce waste, increase productivity, and ultimately positively impact GLIC's bottom line.
Previously, John was with J.P. Morgan Chase's (JPMC) from 2013–2023 in several senior leadership positions of increasing responsibility. As Chief Operating Officer of Chief Technology and Data Offices, he was responsible for overseeing the firmwide strategy, governance, and risk & control guardrails for the firm's public cloud and artificial intelligence & machine learning platforms.
As Chief Operating Officer (COO) of Global Technology (GT) and Chief Information Office (CIO) from 2018–2020, John oversaw Global Technology Strategy, established an Office of the CIO to bring structure and repeatability to the complex CIO role, and standardizing Executive Management Reporting. As CFO, COO, & Head of Strategy, Asset & Wealth Management (AWM) Technology, Operations, & Digital (2014–2018), he led a team of ~150 individuals, helped to orchestrate a >$2.0 billion global budget covering >10,000 in headcount, in >50 locations, with ~700 applications, and >175 vendors.
From 2009–2013 at German multinational investment bank and financial services company Deutsche Bank (NYSE: DB), John held a number of technology and COO leadership positions.
John began his career with Broadridge and the New York Stock Exchange (SIAC); as a management and technology consultant; as a financial services lead for a technology company, BEA Systems (acquired by Oracle); and as a founder of a related system integration firm, Prime Business Consulting.
John graduated with a Masters of Business Administration in Finance & Management and Masters of Science in Computer Science from New York University, as well as a Bachelor of Science, Computer Science from Georgetown University. John is also a certified AWS Machine Learning Specialist, AWS Cloud Solutions Architect, and Scaled Agile Framework (SAFe) 5 Agilist. He is 2025 #1 Amazon Best Selling author of AI: Achieving Impact: Implementing Enterprise AI Via an AI Factory.
He lives in Stamford, CT with his 19- and 17-year-old daughters and his 14-year-old son. He enjoys skiing, sailing, and maximizing his time with friends and family when not at work.
AI: Achieving Impact: Implementing Enterprise AI Via an AI Factory
Format: 60 Minute Keynote (45 mins + Q&A)
This program is perfect for:
- C-level leaders, management, and key stakeholders of an organization looking to accelerate digital transformation and build an AI-driven enterprise today. "AI: Achieving Impact" provides actionable insights to help you move beyond the hype and achieve real-world results.
The audience will leave...
